Version 5.4
Homo sapiens Gene: GULP1
Summary
InnateDB Gene IDBG-77174.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GULP1
Gene Name GULP, engulfment adaptor PTB domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144366
Encoded Proteins
IDBP-77176
GULP, engulfment adaptor PTB domain containing 1
IDBP-293332
GULP, engulfment adaptor PTB domain containing 1
IDBP-293336
GULP, engulfment adaptor PTB domain containing 1
IDBP-293334
GULP, engulfment adaptor PTB domain containing 1
IDBP-293339
GULP, engulfment adaptor PTB domain containing 1
IDBP-293338
GULP, engulfment adaptor PTB domain containing 1
IDBP-293337
GULP, engulfment adaptor PTB domain containing 1
IDBP-293335
GULP, engulfment adaptor PTB domain containing 1
IDBP-293323
GULP, engulfment adaptor PTB domain containing 1
IDBP-387949
GULP, engulfment adaptor PTB domain containing 1
IDBP-387950
GULP, engulfment adaptor PTB domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:188291669-188595931
Strand Forward strand
Band q32.1
Transcripts
ENST00000359135 ENSP00000352047
ENST00000409830 ENSP00000386732
ENST00000409805 ENSP00000387171
ENST00000409580 ENSP00000386289
ENST00000409609 ENSP00000386867
ENST00000409843 ENSP00000387144
ENST00000410051 ENSP00000387013
ENST00000409637 ENSP00000386402
ENST00000409927 ENSP00000386809
ENST00000451191 ENSP00000407131
ENST00000433052 ENSP00000391712
ENST00000486445
ENST00000479019
ENST00000476422
ENST00000467422
ENST00000495745
ENST00000478306
ENST00000496976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
Biological Process
GO:0006869 lipid transport
GO:0006911 phagocytosis, engulfment
GO:0006915 apoptotic process
GO:0007165 signal transduction
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056870
View Gene Order
ENSBTAG00000007141
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
arf6_pathway
Arf6 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.470887 Hs.595546 Hs.712910
RefSeq NM_001252668 NM_001252669 NM_016315 XM_006712590
HUGO
OMIM
CCDS CCDS2295 CCDS58742 CCDS58743
HPRD 12181
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca