Version 5.4
Homo sapiens Gene: MAGEE1
Summary
InnateDB Gene IDBG-77492.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGEE1
Gene Name melanoma antigen family E, 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198934
Encoded Proteins
IDBP-77494
melanoma antigen family E, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:76427724-76431353
Strand Forward strand
Band q13.3
Transcripts
ENST00000361470 ENSP00000354912
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0016010 dystrophin-associated glycoprotein complex
GO:0030425 dendrite
GO:0045211 postsynaptic membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000031227
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.8453
RefSeq NM_020932
HUGO
OMIM
CCDS CCDS14433
HPRD 06583
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca