Version 5.4
Homo sapiens Gene: MAGT1
Summary
InnateDB Gene IDBG-77663.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGT1
Gene Name magnesium transporter 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102158
Encoded Proteins
IDBP-77665
magnesium transporter 1
IDBP-77669
magnesium transporter 1
IDBP-807705
magnesium transporter 1
IDBP-807708
magnesium transporter 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:77826364-77895593
Strand Reverse strand
Band q21.1
Transcripts
ENST00000358075 ENSP00000354649
ENST00000373336 ENSP00000362433
ENST00000476168
ENST00000618282 ENSP00000480732
ENST00000610432 ENSP00000478379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015095 magnesium ion transmembrane transporter activity
Biological Process
GO:0006487 protein N-linked glycosylation
GO:0015693 magnesium ion transport
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0050890 cognition
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005887 integral component of plasma membrane
GO:0008250 oligosaccharyltransferase complex
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031232
View Gene Order
ENSBTAG00000045931
Not yet available
Pathways
NETPATH
REACTOME
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9H0U3
TrEMBL Q96SP2
UniProt Splice Variant
Entrez Gene 84061
UniGene Hs.323562
RefSeq NM_032121
HUGO HGNC:28880
OMIM 300715
CCDS CCDS14436
HPRD 06487
IMGT
EMBL AK027632 AK075394 AK223131 AK314309 AL136636 AL138743 AL356235 AY358691 BC041014 BC060842 CH471104 DQ000004
GenPept AAH41014 AAH60842 AAQ89054 AAY18811 BAB55249 BAC11592 BAD96851 BAG36961 CAB66571 CAH70524 CAI39753 EAW98609 EAW98610
RNA Seq Atlas 84061

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca