Homo sapiens Gene: LST1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-77937.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | LST1 | ||||||||||||||||||
Gene Name | leukocyte specific transcript 1 | ||||||||||||||||||
Synonyms | B144; D6S49E; LST-1 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000204482 | ||||||||||||||||||
Encoded Proteins |
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
leukocyte specific transcript 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
InnateDB Annotation | |||||||||||||||||||
Summary |
LST1 recruits tyrosine-phosphorylated PTPN6 and PTPN11 to the plasma membrane in myeloid leukocytes.
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InnateDB Annotation from Orthologs | |||||||||||||||||||
Summary |
[Mus musculus] Lst1 recruits tyrosine-phosphorylated Ptpn6 and Ptpn11 to the plasma membrane in myeloid leukocytes. (Demonstrated in human)
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Entrez Gene | |||||||||||||||||||
Summary |
The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 6:31586124-31588909 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | p21.33 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||||||||||||||
SwissProt | O00453 | ||||||||||||||||||
TrEMBL | Q5HYT5 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 7940 | ||||||||||||||||||
UniGene | Hs.436066 | ||||||||||||||||||
RefSeq | NM_205837 NM_001166538 NM_007161 NM_205838 NM_205839 NM_205840 XM_006715206 XM_006715209 XM_006715210 XM_006725044 XM_006725047 XM_006725048 XM_006725522 XM_006725525 XM_006725526 XM_006725741 XM_006725744 XM_006725745 XM_006725848 XM_006725851 XM_006725852 XM_006726038 XM_006726041 XM_006726042 XM_006726126 XM_006726129 XM_006726130 | ||||||||||||||||||
HUGO | HGNC:14189 | ||||||||||||||||||
OMIM | 109170 | ||||||||||||||||||
CCDS | CCDS54985 CCDS43450 CCDS4705 CCDS54984 CCDS54986 CCDS54987 | ||||||||||||||||||
HPRD | 00172 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AF000424 AF000425 AF000426 AF129756 AL662801 AL662847 AL929587 AY852266 BA000025 BC103855 BC103856 BX248519 BX927320 CH471081 CR753892 CR759886 CR942185 U00921 Y18486 Y18487 Y18488 Y18489 Y18490 | ||||||||||||||||||
GenPept | AAB57724 AAB86998 AAB86999 AAB87000 AAD18090 AAI03856 AAI03857 AAX45332 BAB63394 CAB59903 CAB59904 CAB59905 CAB59906 CAB60038 CAI17681 CAI17682 CAI17684 CAI17687 CAI18295 CAI18296 CAI18298 CAI18299 CAI18300 CAI18653 CAI18654 CAI18655 CAI18658 CAI18659 CAI41945 CAI41946 CAI41949 CAI41950 CAI41952 CAM26060 CAM45790 CAO72097 CAQ06939 CAQ06940 CAQ06943 CAQ06944 CAQ06946 CAQ06947 CAQ07231 CAQ07232 CAQ07235 CAQ07236 CAQ07238 CAQ07239 CAQ07715 CAQ07716 CAQ07719 CAQ07720 CAQ07722 CAQ07723 CAQ09997 CAQ09998 CAQ10001 CAQ10002 CAQ10004 CAQ10005 EAX03427 EAX03431 | ||||||||||||||||||
RNA Seq Atlas | 7940 | ||||||||||||||||||