Version 5.4
Homo sapiens Gene: MOB4
Summary
InnateDB Gene IDBG-78011.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOB4
Gene Name MOB family member 4, phocein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000115540
Encoded Proteins
IDBP-78013
MOB family member 4, phocein
IDBP-78015
MOB family member 4, phocein
IDBP-293224
MOB family member 4, phocein
IDBP-293227
MOB family member 4, phocein
IDBP-293230
MOB family member 4, phocein
IDBP-388184
MOB family member 4, phocein
IDBP-388185
MOB family member 4, phocein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring HSPE1 (heat shock 10kDa protein 1 (chaperonin 10)) and MOB4 (MOB family member 4, phocein) genes on chromosome 2. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Oct 2011] This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:197515571-197553699
Strand Forward strand
Band q33.1
Transcripts
ENST00000233892 ENSP00000233892
ENST00000323303 ENSP00000315702
ENST00000409355 ENSP00000387043
ENST00000409360 ENSP00000387289
ENST00000409916 ENSP00000387240
ENST00000448447 ENSP00000405354
ENST00000417097 ENSP00000397052
ENST00000497443
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 90 experimentally validated interaction(s) in this database.
Experimentally validated
Total 90 [view]
Protein-Protein 90 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane
GO:0032580 Golgi cisterna membrane
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025979
View Gene Order
ENSBTAG00000019116
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.354972 Hs.633165 Hs.708263
RefSeq NM_001100819 NM_001204094 NM_015387 NM_199482
HUGO
OMIM
CCDS CCDS2321 CCDS2322 CCDS46480
HPRD 10165
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca