Version 5.4
Homo sapiens Protein: MOB4
Summary
InnateDB Protein IDBP-388184.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOB4
Protein Name MOB family member 4, phocein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000405354
InnateDB Gene IDBG-78011 (MOB4)
Protein Structure
UniProt Annotation
Function May play a role in membrane trafficking, specifically in membrane budding reactions. {ECO:0000250}.
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000269PubMed:11319234}. Membrane {ECO:0000269PubMed:11319234}; Peripheral membrane protein {ECO:0000269PubMed:11319234}. Golgi apparatus, Golgi stack membrane {ECO:0000269PubMed:11319234}; Peripheral membrane protein {ECO:0000269PubMed:11319234}. Note=In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 90 experimentally validated interaction(s) in this database.
Experimentally validated
Total 90 [view]
Protein-Protein 90 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0032580 Golgi cisterna membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR005301 Mob1/phocein
PFAM PF03637
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y3A3
PhosphoSite PhosphoSite-Q9Y3A3
TrEMBL B4DM50
UniProt Splice Variant
Entrez Gene 25843
UniGene Hs.708263
RefSeq NP_001094289
HUGO HGNC:17261
OMIM 609361
CCDS CCDS46480
HPRD 10165
IMGT
EMBL AB015441 AC020550 AF093825 AF151853 AF250319 AJ580638 AK027043 AK292938 AK297294 AK297514 AL080070 BC005237 CH471063 CR457371
GenPept AAD34090 AAG44567 AAH05237 AAP97221 AAX93147 BAB15635 BAB19057 BAF85627 BAG59762 BAG59922 CAB45697 CAE45270 CAG33652 EAW70164 EAW70167

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca