Version 5.4
Homo sapiens Gene: PLCL1
Summary
InnateDB Gene IDBG-78092.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLCL1
Gene Name phospholipase C-like 1
Synonyms PLCE; PLCL; PLDL1; PPP1R127; PRIP
Species Homo sapiens
Ensembl Gene ENSG00000115896
Encoded Proteins
IDBP-388195
phospholipase C-like 1
IDBP-388198
phospholipase C-like 1
IDBP-388199
phospholipase C-like 1
IDBP-755574
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:197804702-198572581
Strand Forward strand
Band q33.1
Transcripts
ENST00000435320 ENSP00000410488
ENST00000428675 ENSP00000402861
ENST00000437704 ENSP00000414138
ENST00000487695 ENSP00000457588
ENST00000472193
ENST00000625084
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004629 phospholipase C activity
GO:0004871 signal transducer activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity
GO:0050811 GABA receptor binding
GO:0070679 inositol 1,4,5 trisphosphate binding
Biological Process
GO:0006629 lipid metabolic process
GO:0007165 signal transduction
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0016042 lipid catabolic process
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0035556 intracellular signal transduction
GO:0045087 innate immune response
GO:1900122 positive regulation of receptor binding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038349
View Gene Order
ENSBTAG00000007635
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.153322
RefSeq NM_006226 XM_005246643 XM_005246644
HUGO
OMIM
CCDS CCDS2326
HPRD 07041
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca