Version 5.4
Homo sapiens Gene: NEURL2
Summary
InnateDB Gene IDBG-78406.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEURL2
Gene Name neuralized homolog 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124257
Encoded Proteins
IDBP-78408
neuralized homolog 2 (Drosophila)
IDBP-584522
neuralized homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This human gene represents a non-protein coding RNA due to the presence of an upstream open reading frame (uORF). The uORF is predicted to interfere with translation of the longest ORF, and translation of the uORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The uORF is conserved in primates and some other mammals, but not in mouse and rat. Therefore, the mouse (GeneID:415115) or rat (GeneID: 311633) gene encodes a functional protein. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:45888625-45891287
Strand Reverse strand
Band q13.12
Transcripts
ENST00000372518 ENSP00000361596
ENST00000545238 ENSP00000442383
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0030239 myofibril assembly
GO:0035556 intracellular signal transduction
GO:0045214 sarcomere organization
Cellular Component
GO:0005927 muscle tendon junction
GO:0030891 VCB complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039873
View Gene Order
ENSBTAG00000000961
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 140825
UniGene Hs.517094
RefSeq NM_001278535 NM_080749
HUGO HGNC:16156
OMIM 608597
CCDS CCDS13384
HPRD 16353
IMGT
EMBL
GenPept
RNA Seq Atlas 140825

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca