Version 5.4
Homo sapiens Gene: SRPX2
Summary
InnateDB Gene IDBG-79192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRPX2
Gene Name sushi-repeat containing protein, X-linked 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102359
Encoded Proteins
IDBP-79194
sushi-repeat containing protein, X-linked 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a secreted protein that contains three sushi repeat motifs. The encoded protein may play a role in the development of speech and language centers in the brain. This protein may also be involved in angiogenesis. Mutations in this gene are the cause of bilateral perisylvian polymicrogyria, rolandic epilepsy, speech dyspraxia and mental retardation. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:100644218-100671299
Strand Forward strand
Band q22.1
Transcripts
ENST00000373004 ENSP00000362095
ENST00000481988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0036458 hepatocyte growth factor binding
GO:0042802 identical protein binding
Biological Process
GO:0001525 angiogenesis
GO:0016337 single organismal cell-cell adhesion
GO:0042325 regulation of phosphorylation
GO:0048870 cell motility
GO:0051965 positive regulation of synapse assembly
GO:0071625 vocalization behavior
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0009986 cell surface
GO:0030054 cell junction
GO:0060076 excitatory synapse
GO:0097060 synaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031253
View Gene Order
ENSBTAG00000037686
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.306339
RefSeq NM_014467 XM_005262121
HUGO
OMIM
CCDS CCDS14471
HPRD 06726
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca