Version 5.4
Homo sapiens Gene: SLC2A10
Summary
InnateDB Gene IDBG-79448.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC2A10
Gene Name solute carrier family 2 (facilitated glucose transporter), member 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000197496
Encoded Proteins
IDBP-79450
solute carrier family 2 (facilitated glucose transporter), member 10
IDBP-808151
solute carrier family 2 (facilitated glucose transporter), member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:46709487-46736347
Strand Forward strand
Band q13.12
Transcripts
ENST00000359271 ENSP00000352216
ENST00000486000 ENSP00000478679
ENST00000611837
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005351 sugar:proton symporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015758 glucose transport
GO:0015992 proton transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027661
View Gene Order
ENSBTAG00000002942
Not yet available
Pathways
NETPATH
REACTOME
REACT_19343
Facilitative Na+-independent glucose transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.305971 Hs.597410
RefSeq NM_030777 XM_006723880
HUGO
OMIM
CCDS CCDS13402
HPRD 05851
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca