Version 5.4
Homo sapiens Gene: DRP2
Summary
InnateDB Gene IDBG-79514.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DRP2
Gene Name dystrophin related protein 2
Synonyms DRP-2
Species Homo sapiens
Ensembl Gene ENSG00000102385
Encoded Proteins
IDBP-79516
dystrophin related protein 2
IDBP-240022
dystrophin related protein 2
IDBP-295438
dystrophin related protein 2
IDBP-600102
dystrophin related protein 2
IDBP-601247
dystrophin related protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:101219769-101264497
Strand Forward strand
Band q22.1
Transcripts
ENST00000372916 ENSP00000362007
ENST00000395209 ENSP00000378635
ENST00000402866 ENSP00000385038
ENST00000538510 ENSP00000441051
ENST00000541709 ENSP00000444752
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0007417 central nervous system development
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000223
View Gene Order
ENSBTAG00000001975
Not yet available
Cross-References
SwissProt Q13474
TrEMBL A0A024RCH3
UniProt Splice Variant
Entrez Gene 1821
UniGene Hs.159291
RefSeq NM_001939 XM_006724628 NM_001171184
HUGO HGNC:3032
OMIM 300052
CCDS CCDS14480 CCDS55465
HPRD 02083
IMGT
EMBL AK289825 AK295843 AL022155 BC111695 CH471115 U43519 Z68331 Z70280 Z70281
GenPept AAC50538 AAI11696 BAF82514 BAG58652 CAI42016 CAO03505 EAX02844 EAX02846
RNA Seq Atlas 1821

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca