Version 5.4
Homo sapiens Gene: DOM3Z
Summary
InnateDB Gene IDBG-79767.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOM3Z
Gene Name dom-3 homolog Z (C. elegans)
Synonyms DOM3L; DOM3Z; NG6; RAI1
Species Homo sapiens
Ensembl Gene ENSG00000204348
Encoded Proteins
IDBP-79769
dom-3 homolog Z (C. elegans)
IDBP-79771
dom-3 homolog Z (C. elegans)
IDBP-79773
dom-3 homolog Z (C. elegans)
IDBP-474299
dom-3 homolog Z (C. elegans)
IDBP-475410
dom-3 homolog Z (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:31969810-31972292
Strand Reverse strand
Band p21.33
Transcripts
ENST00000337523 ENSP00000337759
ENST00000375356 ENSP00000364505
ENST00000375349 ENSP00000364498
ENST00000491327
ENST00000485557
ENST00000477826
ENST00000495340 ENSP00000419588
ENST00000473976
ENST00000478221
ENST00000498357
ENST00000480240 ENSP00000418632
ENST00000474587
ENST00000492946
ENST00000487914
ENST00000460058
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0003729 mRNA binding
GO:0008409 5'-3' exonuclease activity
GO:0034353 RNA pyrophosphohydrolase activity
Biological Process
GO:0006402 mRNA catabolic process
GO:0008152 metabolic process
GO:0050779 RNA destabilization
GO:0071028 nuclear mRNA surveillance
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040482
View Gene Order
ENSBTAG00000005588
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.153299 Hs.706492
RefSeq NM_005510 XM_006715005 XM_006715007 XM_006725474 XM_006725476 XM_006725688 XM_006725898 XM_006725900 XM_006725985 XM_006725987 XM_006726078 XM_006726080
HUGO
OMIM
CCDS CCDS4732
HPRD 16186
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca