Version 5.4
Homo sapiens Protein: DOM3Z
Summary
InnateDB Protein IDBP-79769.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOM3Z
Protein Name dom-3 homolog Z (C. elegans)
Synonyms DOM3L; DOM3Z; NG6; RAI1;
Species Homo sapiens
Ensembl Protein ENSP00000337759
InnateDB Gene IDBG-79767 (DOM3Z)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0003729 mRNA binding
GO:0008409 5'-3' exonuclease activity
GO:0034353 RNA pyrophosphohydrolase activity
Biological Process
GO:0006402 mRNA catabolic process
GO:0008152 metabolic process
GO:0050779 RNA destabilization
GO:0071028 nuclear mRNA surveillance
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR013961 RAI1-like
PFAM PF08652
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O77932
PhosphoSite PhosphoSite-O77932
TrEMBL A0A024RCW8
UniProt Splice Variant
Entrez Gene 1797
UniGene Hs.706492
RefSeq NP_005501
HUGO HGNC:2992
OMIM 605996
CCDS CCDS4732
HPRD 16186
IMGT
EMBL AF019413 AF059252 AF059253 AF059254 AL049547 AL645922 AL662849 AL844853 BC009344 BC019083 CH471081 CR753822 CR753845 CR759782
GenPept AAB67983 AAC78603 AAC78604 AAC78605 AAH09344 AAH19083 CAB89305 CAB89306 CAI17465 CAI41864 CAM26055 CAQ07122 CAQ09281 CAQ10912 EAX03558 EAX03561 EAX03562 EAX03565

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca