Version 5.4
Homo sapiens Gene: BHLHB9
Summary
InnateDB Gene IDBG-80346.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BHLHB9
Gene Name basic helix-loop-helix domain containing, class B, 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198908
Encoded Proteins
IDBP-80350
basic helix-loop-helix domain containing, class B, 9
IDBP-80352
basic helix-loop-helix domain containing, class B, 9
IDBP-378170
basic helix-loop-helix domain containing, class B, 9
IDBP-378176
basic helix-loop-helix domain containing, class B, 9
IDBP-378178
basic helix-loop-helix domain containing, class B, 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of a gene family which encodes proteins with a basic helix-loop-helix domain. Other members of this gene family encode proteins which function as transcription factors, either enhancing or inhibiting transcription depending on the activity of other DNA binding proteins. The coding region of this gene is located entirely within the terminal exon. The encoded protein may be involved in the survival of neurons (PMID: 15034937). Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:102720688-102753540
Strand Forward strand
Band q22.1
Transcripts
ENST00000361229 ENSP00000354675
ENST00000372735 ENSP00000361820
ENST00000457056 ENSP00000403226
ENST00000447531 ENSP00000405893
ENST00000448867 ENSP00000391722
ENST00000483294
ENST00000486988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007611 learning or memory
GO:0043524 negative regulation of neuron apoptotic process
GO:0050769 positive regulation of neurogenesis
GO:0051965 positive regulation of synapse assembly
GO:0061003 positive regulation of dendritic spine morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000072964
View Gene Order
Cross-References
SwissProt Q6PI77
TrEMBL
UniProt Splice Variant
Entrez Gene 80823
UniGene Hs.4276 Hs.603894
RefSeq NM_001142524 NM_001142525 NM_001142526 NM_001142527 NM_001142528 NM_001142529 NM_001142530 NM_030639
HUGO HGNC:29353
OMIM 300921
CCDS CCDS14502
HPRD 10028
IMGT
EMBL AB051488 AF547055 AL035427 BC041409 CH471190
GenPept AAH41409 AAQ12077 BAB21792 CAI43061 EAW54726
RNA Seq Atlas 80823

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca