Version 5.4
Homo sapiens Gene: GLRA4
Summary
InnateDB Gene IDBG-80816.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLRA4
Gene Name glycine receptor, alpha 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188828
Encoded Proteins
IDBP-80818
glycine receptor, alpha 4
IDBP-378399
glycine receptor, alpha 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which has a neurotransmitter-gated ion-channel ligand binding domain. The encoded protein is very similar to a mouse protein which is a subunit of the retinal glycine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:103707224-103728655
Strand Reverse strand
Band q22.2
Transcripts
ENST00000372617 ENSP00000361700
ENST00000436213 ENSP00000412480
ENST00000480725
ENST00000469567
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005254 chloride channel activity
GO:0016594 glycine binding
GO:0022824 transmitter-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0034707 chloride channel complex
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018595
View Gene Order
ENSBTAG00000003320
Not yet available
Pathways
NETPATH
REACTOME
REACT_25387
Ligand-gated ion channel transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.533289
RefSeq NM_001024452
HUGO
OMIM
CCDS CCDS43980
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca