InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: KCNG1

Summary

InnateDB Gene

IDBG-81211.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNG1

Gene Name

potassium voltage-gated channel, subfamily G, member 1

Synonyms

K13; KCNG; kH2; KV6.1

Species

Homo sapiens

Ensembl Gene

ENSG00000026559

Encoded Proteins

IDBP-81213

potassium voltage-gated channel, subfamily G, member 1

IDBP-378534

potassium voltage-gated channel, subfamily G, member 1

IDBP-378539

potassium voltage-gated channel, subfamily G, member 1

IDBP-378540

potassium voltage-gated channel, subfamily G, member 1

IDBP-378542

potassium voltage-gated channel, subfamily G, member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 20:51003656-51023129

Strand

Reverse strand

Band

q13.13

Transcripts

ENST00000371571	ENSP00000360626
ENST00000439216	ENSP00000394075
ENST00000424171	ENSP00000394093
ENST00000433903	ENSP00000408116
ENST00000447736	ENSP00000396058

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005267	potassium channel activity
GO:0005515	protein binding

Biological Process

GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0007268	synaptic transmission
GO:0034765	regulation of ion transmembrane transport
GO:0051260	protein homooligomerization
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000074575

View Gene Order

ENSBTAG00000003398

Not yet available

Pathways

NETPATH

REACTOME

REACT_75770

Voltage gated Potassium channels pathway

REACT_13685

Neuronal System pathway

REACT_75908

Potassium Channels pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.735151

RefSeq

NM_002237 XM_006723785

HUGO

OMIM

CCDS

CCDS13436

HPRD

04809

IMGT

EMBL

GenPept

RNA Seq Atlas