InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KCNG1

Summary

InnateDB Protein

IDBP-378534.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNG1

Protein Name

potassium voltage-gated channel, subfamily G, member 1

Synonyms

K13; KCNG; kH2; KV6.1;

Species

Homo sapiens

Ensembl Protein

ENSP00000394075

InnateDB Gene

IDBG-81211 (KCNG1)

Protein Structure

UniProt Annotation

Function

Probable potassium channel subunit. May need to associate with another protein to form a functional channel. May modulate channel activity.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Detected in brain and placenta, and at much lower levels in kidney and pancreas.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005249	voltage-gated potassium channel activity
GO:0005515	protein binding

Biological Process

GO:0051260	protein homooligomerization
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0008076	voltage-gated potassium channel complex
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR003091 Potassium channel
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR003969 Potassium channel, voltage dependent, Kv6
IPR003971 Potassium channel, voltage dependent, Kv9
IPR003974 Potassium channel, voltage dependent, Kv3
IPR011333 BTB/POZ fold

PFAM

PF02214

PRINTS

PR00169
PR01492
PR01494
PR01498

PIRSF

SMART

SM00225

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt