Version 5.4
Homo sapiens Gene: RIPPLY1
Summary
InnateDB Gene IDBG-81277.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIPPLY1
Gene Name ripply1 homolog (zebrafish)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147223
Encoded Proteins
IDBP-81281
ripply1 homolog (zebrafish)
IDBP-378697
ripply1 homolog (zebrafish)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein similar to a zebrafish protein which acts as a transcriptional repressor in and is required for somite segmentation in zebrafish embryos (PMID: 16326386). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:106900063-106903335
Strand Reverse strand
Band q22.3
Transcripts
ENST00000276173 ENSP00000276173
ENST00000411805 ENSP00000400539
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001757 somite specification
GO:0006351 transcription, DNA-templated
GO:0007219 Notch signaling pathway
GO:0009880 embryonic pattern specification
GO:0010468 regulation of gene expression
GO:0032525 somite rostral/caudal axis specification
GO:0045892 negative regulation of transcription, DNA-templated
GO:0060349 bone morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000072945
View Gene Order
ENSBTAG00000044115
Not yet available
Cross-References
SwissProt Q0D2K3
TrEMBL
UniProt Splice Variant
Entrez Gene 92129
UniGene Hs.334726
RefSeq NM_138382 NM_001171706
HUGO HGNC:25117
OMIM 300575
CCDS CCDS48145 CCDS55471
HPRD
IMGT
EMBL AL591849 BC105691 BC105692 BC110436 BC127250 CH471120
GenPept AAI05692 AAI05693 AAI10437 AAI27251 CAI40159 CAI40160 EAX02733
RNA Seq Atlas 92129

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca