Version 5.4
Homo sapiens Protein: RIPPLY1
Summary
InnateDB Protein IDBP-378697.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIPPLY1
Protein Name ripply1 homolog (zebrafish)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000400539
InnateDB Gene IDBG-81277 (RIPPLY1)
Protein Structure
UniProt Annotation
Function Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites (By similarity). {ECO:0000250UniProtKB:Q2WG80}.
Subcellular Localization Nucleus {ECO:0000250UniProtKB:Q2WG80}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001757 somite specification
GO:0006351 transcription, DNA-templated
GO:0009880 embryonic pattern specification
GO:0032525 somite rostral/caudal axis specification
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0D2K3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 92129
UniGene Hs.334726
RefSeq NP_001165177
HUGO HGNC:25117
OMIM 300575
CCDS CCDS55471
HPRD
IMGT
EMBL AL591849 BC105691 BC105692 BC110436 BC127250 CH471120
GenPept AAI05692 AAI05693 AAI10437 AAI27251 CAI40159 CAI40160 EAX02733

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca