Version 5.4
Homo sapiens Gene: ZFP37
Summary
InnateDB Gene IDBG-81470.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZFP37
Gene Name zinc finger protein 37 homolog (mouse)
Synonyms zfp-37; ZNF906
Species Homo sapiens
Ensembl Gene ENSG00000136866
Encoded Proteins
IDBP-81472
zinc finger protein 37 homolog (mouse)
IDBP-594054
zinc finger protein 37 homolog (mouse)
IDBP-587294
zinc finger protein 37 homolog (mouse)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transcription factor that belongs to a large family of zinc finger proteins. A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:113038380-113056759
Strand Reverse strand
Band q32
Transcripts
ENST00000374227 ENSP00000363344
ENST00000555206 ENSP00000451310
ENST00000553380 ENSP00000452552
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028389
View Gene Order
ENSBTAG00000045868
Not yet available
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9Y6Q3
TrEMBL
UniProt Splice Variant
Entrez Gene 7539
UniGene Hs.150406
RefSeq NM_003408 NM_001282515 NM_001282518
HUGO HGNC:12863
OMIM 602951
CCDS CCDS6787 CCDS65109 CCDS65110
HPRD 04258
IMGT
EMBL AF022158 AK301275 AL162588 BC126390 CH878453
GenPept AAC28425 AAI26391 BAG62836 EAW50556
RNA Seq Atlas 7539

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca