InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZFP37

Summary

InnateDB Protein

IDBP-587294.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZFP37

Protein Name

zinc finger protein 37 homolog (mouse)

Synonyms

zfp-37; ZNF906;

Species

Homo sapiens

Ensembl Protein

ENSP00000452552

InnateDB Gene

IDBG-81470 (ZFP37)

Protein Structure

UniProt Annotation

Function

May be involved in transcriptional regulation.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed at low level in several tissues including fetal cartilage.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	0
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like

PFAM

PF01352
PF00096

PRINTS

PIRSF

SMART

SM00349
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y6Q3

PhosphoSite

PhosphoSite-Q9Y6Q3

TrEMBL

UniProt Splice Variant

Entrez Gene

7539

UniGene

Hs.150406

RefSeq

NP_001269444

HUGO

HGNC:12863

OMIM

602951

CCDS

CCDS65110

HPRD

04258

IMGT

EMBL

AF022158 AK301275 AL162588 BC126390 CH878453

GenPept

AAC28425 AAI26391 BAG62836 EAW50556