Version 5.4
Homo sapiens Gene: DNPEP
Summary
InnateDB Gene IDBG-81550.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNPEP
Gene Name aspartyl aminopeptidase
Synonyms ASPEP; DAP
Species Homo sapiens
Ensembl Gene ENSG00000123992
Encoded Proteins
IDBP-81554
aspartyl aminopeptidase
IDBP-81558
aspartyl aminopeptidase
IDBP-81560
aspartyl aminopeptidase
IDBP-81562
aspartyl aminopeptidase
IDBP-81564
aspartyl aminopeptidase
IDBP-389068
aspartyl aminopeptidase
IDBP-389069
aspartyl aminopeptidase
IDBP-389070
aspartyl aminopeptidase
IDBP-389071
aspartyl aminopeptidase
IDBP-481774
aspartyl aminopeptidase
IDBP-481000
aspartyl aminopeptidase
IDBP-476689
aspartyl aminopeptidase
IDBP-474722
aspartyl aminopeptidase
IDBP-476541
aspartyl aminopeptidase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:219373546-219400022
Strand Reverse strand
Band q35
Transcripts
ENST00000273075 ENSP00000273075
ENST00000373972 ENSP00000363083
ENST00000373966 ENSP00000363077
ENST00000373963 ENSP00000363074
ENST00000322176 ENSP00000317252
ENST00000457935 ENSP00000410684
ENST00000429013 ENSP00000400944
ENST00000434339 ENSP00000412003
ENST00000430206 ENSP00000414739
ENST00000523282 ENSP00000431076
ENST00000490371
ENST00000488051
ENST00000462779
ENST00000488881
ENST00000521459 ENSP00000429960
ENST00000460963
ENST00000522421
ENST00000520694 ENSP00000429468
ENST00000523527
ENST00000519698 ENSP00000428531
ENST00000519905 ENSP00000430630
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026209
View Gene Order
ENSBTAG00000021514
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.258551
RefSeq NM_012100 XM_005246430 XM_005246431 XM_005246432
HUGO
OMIM
CCDS CCDS42823
HPRD 09924
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca