InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DNPEP

Summary

InnateDB Protein

IDBP-81554.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DNPEP

Protein Name

aspartyl aminopeptidase

Synonyms

ASPEP; DAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000273075

InnateDB Gene

IDBG-81550 (DNPEP)

Protein Structure

UniProt Annotation

Function

Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Ubiquitous.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004177	aminopeptidase activity
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0006518	peptide metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

InterPro

IPR001948 Peptidase M18
IPR008007 Peptidase M42

PFAM

PF02127
PF05343

PRINTS

PR00932

PIRSF

PIRSF001123

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9ULA0

PhosphoSite

PhosphoSite-Q53SB6

TrEMBL

E5RJ35

UniProt Splice Variant

Entrez Gene

23549

UniGene

Hs.258551

RefSeq

NP_036232

HUGO

HGNC:2981

OMIM

611367

CCDS

CCDS42823

HPRD

09924

IMGT

EMBL

AC053503 AF005050 AK001977 BC000653 CH471063

GenPept

AAD01211 AAH00653 BAA92014 EAW70729 EAW70732 EAW70738