Version 5.4
Homo sapiens Gene: BCAS1
Summary
InnateDB Gene IDBG-81598.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCAS1
Gene Name breast carcinoma amplified sequence 1
Synonyms AIBC1; NABC1
Species Homo sapiens
Ensembl Gene ENSG00000064787
Encoded Proteins
IDBP-81600
breast carcinoma amplified sequence 1
IDBP-81602
breast carcinoma amplified sequence 1
IDBP-238482
breast carcinoma amplified sequence 1
IDBP-378799
breast carcinoma amplified sequence 1
IDBP-378808
breast carcinoma amplified sequence 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:53936777-54070594
Strand Reverse strand
Band q13.2
Transcripts
ENST00000371440 ENSP00000360495
ENST00000371435 ENSP00000360490
ENST00000395961 ENSP00000379290
ENST00000448484 ENSP00000396361
ENST00000422805 ENSP00000399936
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000013523
View Gene Order
ENSBTAG00000000835
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.731932
RefSeq NM_003657 XM_005260596
HUGO
OMIM
CCDS CCDS13444
HPRD 04273
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca