Version 5.4
Homo sapiens Gene: SLC4A3
Summary
InnateDB Gene IDBG-82057.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC4A3
Gene Name solute carrier family 4, anion exchanger, member 3
Synonyms AE3; SLC2C
Species Homo sapiens
Ensembl Gene ENSG00000114923
Encoded Proteins
IDBP-82059
solute carrier family 4, anion exchanger, member 3
IDBP-82061
solute carrier family 4, anion exchanger, member 3
IDBP-82063
solute carrier family 4, anion exchanger, member 3
IDBP-82067
solute carrier family 4, anion exchanger, member 3
IDBP-389101
solute carrier family 4, anion exchanger, member 3
IDBP-389103
solute carrier family 4, anion exchanger, member 3
IDBP-389104
solute carrier family 4, anion exchanger, member 3
IDBP-389105
solute carrier family 4, anion exchanger, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:219627327-219641980
Strand Forward strand
Band q35
Transcripts
ENST00000273063 ENSP00000273063
ENST00000358055 ENSP00000350756
ENST00000317151 ENSP00000314006
ENST00000373760 ENSP00000362865
ENST00000425141 ENSP00000396863
ENST00000413743 ENSP00000414722
ENST00000416910 ENSP00000403160
ENST00000444906 ENSP00000398628
ENST00000497589
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005452 inorganic anion exchanger activity
GO:0008509 anion transmembrane transporter activity
GO:0015301 anion:anion antiporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006820 anion transport
GO:0015701 bicarbonate transport
GO:0051453 regulation of intracellular pH
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006576
View Gene Order
ENSBTAG00000014975
Not yet available
Pathways
NETPATH
REACTOME
REACT_19298
Bicarbonate transporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8WD49
UniProt Splice Variant
Entrez Gene 6508
UniGene Hs.1176 Hs.684906
RefSeq NM_005070 NM_201574 XM_005246789 XM_006712703
HUGO HGNC:11029
OMIM 106195
CCDS CCDS2445 CCDS2446
HPRD 00109
IMGT
EMBL AC009955
GenPept
RNA Seq Atlas 6508

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca