Version 5.4
Homo sapiens Gene: PPP1R3C
Summary
InnateDB Gene IDBG-82295.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R3C
Gene Name protein phosphatase 1, regulatory subunit 3C
Synonyms PPP1R5
Species Homo sapiens
Ensembl Gene ENSG00000119938
Encoded Proteins
IDBP-82297
protein phosphatase 1, regulatory subunit 3C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a regulatory subunit of protein phosphatase-1 (PP1). PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities: neuronal, muscular, RNA splicing, protein synthesis, cell death, and glycogen metabolism, to name just a few. By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or to respond to extracellular signals. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:91628442-91633054
Strand Reverse strand
Band q23.32
Transcripts
ENST00000238994 ENSP00000238994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0019903 protein phosphatase binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0005978 glycogen biosynthetic process
GO:0006006 glucose metabolic process
GO:0016311 dephosphorylation
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000067279
View Gene Order
ENSBTAG00000014831
Not yet available
Pathways
NETPATH
REACTOME
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_169208
Glycogen synthesis pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_723
Glucose metabolism pathway
REACT_200833
Glycogen storage diseases pathway
KEGG
hsa04910
Insulin signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9UQK1
TrEMBL B4DRR5
UniProt Splice Variant
Entrez Gene 5507
UniGene Hs.303090 Hs.700228
RefSeq NM_005398
HUGO HGNC:9293
OMIM 602999
CCDS CCDS7416
HPRD
IMGT
EMBL AF110824 AK299392 AK313149 AL359986 BC012625 BX537399 CH471066 Y18207
GenPept AAD33215 AAH12625 BAG35967 BAG61377 CAA77082 CAD97641 CAH69995 EAW50107
RNA Seq Atlas 5507

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca