Version 5.4
Homo sapiens Gene: CAB39
Summary
InnateDB Gene IDBG-82966.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAB39
Gene Name calcium binding protein 39
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135932
Encoded Proteins
IDBP-82968
calcium binding protein 39
IDBP-292939
calcium binding protein 39
IDBP-292936
calcium binding protein 39
IDBP-813750
calcium binding protein 39
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:230712845-230821075
Strand Forward strand
Band q37.1
Transcripts
ENST00000258418 ENSP00000258418
ENST00000409788 ENSP00000386238
ENST00000410084 ENSP00000386642
ENST00000484398
ENST00000478152
ENST00000493540
ENST00000614925 ENSP00000483459
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004674 protein serine/threonine kinase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0030295 protein kinase activator activity
GO:0043539 protein serine/threonine kinase activator activity
Biological Process
GO:0006468 protein phosphorylation
GO:0007050 cell cycle arrest
GO:0008286 insulin receptor signaling pathway
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0023014 signal transduction by phosphorylation
GO:0032147 activation of protein kinase activity
GO:0035556 intracellular signal transduction
GO:0051291 protein heterooligomerization
GO:0071476 cellular hypotonic response
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:1901017 negative regulation of potassium ion transmembrane transporter activity
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:2000681 negative regulation of rubidium ion transport
GO:2000687 negative regulation of rubidium ion transmembrane transporter activity
Cellular Component
GO:0005829 cytosol
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036707
View Gene Order
ENSBTAG00000040055
Not yet available
Pathways
NETPATH
REACTOME
REACT_21285
Regulation of AMPK activity via LKB1 pathway
REACT_6838
mTOR signalling pathway
REACT_976
PI3K Cascade pathway
REACT_498
Signaling by Insulin receptor pathway
REACT_150203
IRS-related events triggered by IGF1R pathway
REACT_150359
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
REACT_21387
Energy dependent regulation of mTOR by LKB1-AMPK pathway
REACT_456
PKB-mediated events pathway
REACT_111102
Signal Transduction pathway
REACT_332
IRS-mediated signalling pathway
REACT_1195
Insulin receptor signalling cascade pathway
REACT_762
IRS-related events pathway
REACT_150210
IGF1R signaling cascade pathway
KEGG
hsa04150
mTOR signaling pathway pathway
INOH
PID NCI
lkb1_pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001130849 NM_001130850 NM_016289
HUGO
OMIM
CCDS CCDS2478
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca