Version 5.4
Homo sapiens Gene: LEMD2
Summary
InnateDB Gene IDBG-83257.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LEMD2
Gene Name LEM domain containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000161904
Encoded Proteins
IDBP-83259
LEM domain containing 2
IDBP-375965
LEM domain containing 2
IDBP-375966
LEM domain containing 2
IDBP-476178
LEM domain containing 2
IDBP-483998
LEM domain containing 2
IDBP-485214
LEM domain containing 2
IDBP-474982
LEM domain containing 2
IDBP-809057
LEM domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:33771202-33789136
Strand Reverse strand
Band p21.31
Transcripts
ENST00000293760 ENSP00000293760
ENST00000421671 ENSP00000398733
ENST00000442696 ENSP00000408524
ENST00000506578 ENSP00000423715
ENST00000511171
ENST00000508327 ENSP00000421704
ENST00000510598
ENST00000504692 ENSP00000421112
ENST00000502643
ENST00000513832
ENST00000512368
ENST00000513701 ENSP00000423619
ENST00000514636
ENST00000614475 ENSP00000478539
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0035914 skeletal muscle cell differentiation
GO:0043409 negative regulation of MAPK cascade
Cellular Component
GO:0005639 integral component of nuclear inner membrane
GO:0016020 membrane
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044857
View Gene Order
ENSBTAG00000015538
Not yet available
Pathways
NETPATH
REACTOME
REACT_160251
Clearance of Nuclear Envelope Membranes from Chromatin pathway
REACT_160242
Initiation of Nuclear Envelope Reformation pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_765
Mitotic Prophase pathway
REACT_160113
Nuclear Envelope Reassembly pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_200828
Depolymerisation of the Nuclear Lamina pathway
REACT_160255
Nuclear Envelope Breakdown pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.444845
RefSeq NM_001143944 NM_181336
HUGO
OMIM
CCDS CCDS47411 CCDS4785
HPRD 13984
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca