Version 5.4
Homo sapiens Gene: TXNDC2
Summary
InnateDB Gene IDBG-833.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TXNDC2
Gene Name thioredoxin domain containing 2 (spermatozoa)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168454
Encoded Proteins
IDBP-835
thioredoxin domain containing 2 (spermatozoa)
IDBP-837
thioredoxin domain containing 2 (spermatozoa)
IDBP-585200
thioredoxin domain containing 2 (spermatozoa)
IDBP-726493
IDBP-806902
thioredoxin domain containing 2 (spermatozoa)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:9885726-9889275
Strand Forward strand
Band p11.22
Transcripts
ENST00000357775 ENSP00000350419
ENST00000306084 ENSP00000304908
ENST00000426718
ENST00000536353 ENSP00000437393
ENST00000584255 ENSP00000464677
ENST00000611534 ENSP00000483261
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0004791 thioredoxin-disulfide reductase activity
GO:0015035 protein disulfide oxidoreductase activity
GO:0045735 nutrient reservoir activity
Biological Process
GO:0006457 protein folding
GO:0006662 glycerol ether metabolic process
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0001520 outer dense fiber
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0031514 motile cilium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000050612
View Gene Order
ENSBTAG00000017276
Not yet available
Cross-References
SwissProt Q86VQ3
TrEMBL F5H6S7 J3QSG5
UniProt Splice Variant
Entrez Gene 84203
UniGene Hs.742985 Hs.98712
RefSeq NM_001098529 NM_032243
HUGO HGNC:16470
OMIM
CCDS CCDS11846 CCDS42414
HPRD
IMGT
EMBL AC006238 AF080095 AK097656 AL136742 BC050132 EF560747
GenPept AAH50132 AAK94950 ABQ59057 BAC05133 CAB66676
RNA Seq Atlas 84203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca