Version 5.4
Homo sapiens Gene: CHTF18
Summary
InnateDB Gene IDBG-8353.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHTF18
Gene Name CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127586
Encoded Proteins
IDBP-8355
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-8357
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-362209
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-362210
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-362213
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-746036
IDBP-753626
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:788622-800737
Strand Forward strand
Band p13.3
Transcripts
ENST00000317063 ENSP00000313029
ENST00000262315 ENSP00000262315
ENST00000440239 ENSP00000399111
ENST00000455171 ENSP00000406252
ENST00000426047 ENSP00000412015
ENST00000464728
ENST00000479976
ENST00000471202
ENST00000491530
ENST00000484349
ENST00000461268
ENST00000493715
ENST00000498439
ENST00000563545 ENSP00000456998
ENST00000570058
ENST00000565787
ENST00000569270 ENSP00000454679
ENST00000567620
ENST00000564940
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0007049 cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019214
View Gene Order
ENSBTAG00000019743
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.153850
RefSeq NM_022092 XM_005255470 XM_005255471
HUGO
OMIM
CCDS CCDS45371
HPRD 13059
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca