Version 5.4
Mus musculus Gene: Chtf18
Summary
InnateDB Gene IDBG-152447.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chtf18
Gene Name CTF18, chromosome transmission fidelity factor 18
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000019214
Encoded Proteins
IDBP-152449
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-623925
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-623940
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-623942
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
IDBP-623945
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127586:
CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:25718926-25727419
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000048054 ENSMUSP00000043896
ENSMUST00000170575 ENSMUSP00000131366
ENSMUST00000168914
ENSMUST00000167940 ENSMUSP00000131349
ENSMUST00000169767 ENSMUSP00000129694
ENSMUST00000168060
ENSMUST00000170070 ENSMUSP00000131768
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0007049 cell cycle
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000127586
View Gene Order
ENSBTAG00000019743
Not yet available
Cross-References
SwissProt
TrEMBL E9PVJ3
UniProt Splice Variant
Entrez Gene 214901
UniGene Mm.102540
RefSeq NM_145409 XM_006524017
OMIM
CCDS CCDS28523
HPRD
IMGT
MGI ID MGI:2384887
MGI Symbol Chtf18
EMBL AC134908
GenPept
RNA Seq Atlas 214901

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca