Version 5.4
Homo sapiens Gene: TRPM8
Summary
InnateDB Gene IDBG-83904.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRPM8
Gene Name transient receptor potential cation channel, subfamily M, member 8
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144481
Encoded Proteins
IDBP-83906
transient receptor potential cation channel, subfamily M, member 8
IDBP-83908
transient receptor potential cation channel, subfamily M, member 8
IDBP-292882
transient receptor potential cation channel, subfamily M, member 8
IDBP-389414
transient receptor potential cation channel, subfamily M, member 8
IDBP-389415
transient receptor potential cation channel, subfamily M, member 8
IDBP-389416
transient receptor potential cation channel, subfamily M, member 8
IDBP-389417
transient receptor potential cation channel, subfamily M, member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:233917398-234019522
Strand Forward strand
Band q37.1
Transcripts
ENST00000355722 ENSP00000347956
ENST00000324695 ENSP00000323926
ENST00000409625 ENSP00000386771
ENST00000444298 ENSP00000396745
ENST00000433712 ENSP00000404423
ENST00000456930 ENSP00000414198
ENST00000439148 ENSP00000390609
ENST00000479332
ENST00000487033
ENST00000490797
ENST00000477698
ENST00000475044
ENST00000477103
ENST00000466594
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0009266 response to temperature stimulus
GO:0009409 response to cold
GO:0034220 ion transmembrane transport
GO:0050955 thermoception
GO:0051289 protein homotetramerization
GO:0055085 transmembrane transport
GO:0070207 protein homotrimerization
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045121 membrane raft
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036251
View Gene Order
ENSBTAG00000014652
Not yet available
Pathways
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.366053 Hs.607730
RefSeq NM_024080
HUGO
OMIM
CCDS CCDS33407
HPRD 09454
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca