Version 5.4
Mus musculus Gene: Trpm8
Summary
InnateDB Gene IDBG-179466.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trpm8
Gene Name transient receptor potential cation channel, subfamily M, member 8
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036251
Encoded Proteins
IDBP-179468
transient receptor potential cation channel, subfamily M, member 8
IDBP-254552
transient receptor potential cation channel, subfamily M, member 8
IDBP-628147
transient receptor potential cation channel, subfamily M, member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144481:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:88277661-88389293
Strand Forward strand
Band D
Transcripts
ENSMUST00000040210 ENSMUSP00000036991
ENSMUST00000113114 ENSMUSP00000108739
ENSMUST00000148138
ENSMUST00000171176 ENSMUSP00000131209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0009266 response to temperature stimulus
GO:0009409 response to cold
GO:0034220 ion transmembrane transport
GO:0050955 thermoception
GO:0051289 protein homotetramerization
GO:0055085 transmembrane transport
GO:0070207 protein homotrimerization
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045121 membrane raft
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000144481
View Gene Order
ENSBTAG00000014652
Not yet available
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_227861
TRP channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.218753
RefSeq NM_134252 XM_006529225 XM_006529226 XM_006529227 XM_006529228
OMIM
CCDS CCDS48316
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca