Version 5.4
Homo sapiens Gene: LMF1
Summary
InnateDB Gene IDBG-8415.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMF1
Gene Name lipase maturation factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000103227
Encoded Proteins
IDBP-8417
lipase maturation factor 1
IDBP-596663
lipase maturation factor 1
IDBP-598862
lipase maturation factor 1
IDBP-749647
IDBP-746322
IDBP-749541
IDBP-746342
IDBP-753994
IDBP-750266
IDBP-751960
IDBP-746451
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene resides in the endoplasmic reticulum, and is involved in the maturation and transport of lipoprotein lipase through the secretory pathway. Mutations in this gene are associated with combined lipase deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:853634-981318
Strand Reverse strand
Band p13.3
Transcripts
ENST00000262301 ENSP00000262301
ENST00000543238 ENSP00000437418
ENST00000545827 ENSP00000443820
ENST00000568897 ENSP00000458135
ENST00000566609
ENST00000565198
ENST00000570014 ENSP00000454672
ENST00000562380 ENSP00000455715
ENST00000568964 ENSP00000456631
ENST00000562226 ENSP00000455833
ENST00000565276 ENSP00000455930
ENST00000569516
ENST00000568268
ENST00000570168
ENST00000566627 ENSP00000455162
ENST00000567595 ENSP00000457725
ENST00000611669
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0009306 protein secretion
GO:0033578 protein glycosylation in Golgi
GO:0034382 chylomicron remnant clearance
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0051604 protein maturation
GO:0090181 regulation of cholesterol metabolic process
GO:0090207 regulation of triglyceride metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000002279
View Gene Order
ENSBTAG00000019745
Not yet available
Cross-References
SwissProt
TrEMBL B4DFZ0
UniProt Splice Variant
Entrez Gene 64788
UniGene
RefSeq NM_022773 XM_006720926 XM_006720928
HUGO HGNC:14154
OMIM 611761
CCDS CCDS45373
HPRD 07789
IMGT
EMBL AC009041 AK294329 AL008727 AL031008 AL031716 Z93041
GenPept BAG57601
RNA Seq Atlas 64788

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca