Version 5.4
| Homo sapiens Gene: UBE2J2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-84749.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | UBE2J2 | ||||||||||||||||||
| Gene Name | ubiquitin-conjugating enzyme E2, J2 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000160087 | ||||||||||||||||||
| Encoded Proteins |
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
ubiquitin-conjugating enzyme E2, J2
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 1:1253909-1273885 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | p36.33 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
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| KEGG |
Ubiquitin mediated proteolysis pathway
Parkinson's disease pathway
Protein processing in endoplasmic reticulum pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | B1AMF0 D6R9H0 D6RB84 D6RD90 D6REN4 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 118424 | ||||||||||||||||||
| UniGene | Hs.191987 | ||||||||||||||||||
| RefSeq | NM_058167 NM_194315 NM_194457 NM_194458 XM_006710334 | ||||||||||||||||||
| HUGO | HGNC:19268 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS14 CCDS15 CCDS16 | ||||||||||||||||||
| HPRD | 15600 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AL162741 | ||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 118424 | ||||||||||||||||||