Version 5.4
Mus musculus Gene: Ube2j2
Summary
InnateDB Gene IDBG-208149.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ube2j2
Gene Name ubiquitin-conjugating enzyme E2J 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000023286
Encoded Proteins
IDBP-208151
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-208153
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-270564
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-270566
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-270568
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-400068
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-539830
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-534016
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
IDBP-627273
ubiquitin-conjugating enzyme E2, J2 homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160087:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:155943831-155959604
Strand Forward strand
Band E2
Transcripts
ENSMUST00000024056 ENSMUSP00000024056
ENSMUST00000103175 ENSMUSP00000099464
ENSMUST00000105583 ENSMUSP00000101208
ENSMUST00000105582 ENSMUSP00000101207
ENSMUST00000105581 ENSMUSP00000101206
ENSMUST00000118192 ENSMUSP00000112785
ENSMUST00000136492 ENSMUSP00000120855
ENSMUST00000150846
ENSMUST00000152536 ENSMUSP00000114235
ENSMUST00000138218
ENSMUST00000151892
ENSMUST00000124092
ENSMUST00000166489 ENSMUSP00000127712
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0006986 response to unfolded protein
GO:0008152 metabolic process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160087
View Gene Order
ENSBTAG00000015882
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04120
Ubiquitin mediated proteolysis pathway
mmu05012
Parkinson's disease pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
hsa05012
Parkinson's disease pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.266575 Mm.371673
RefSeq NM_001039157 NM_001039158 NM_001039159 NM_001284312 NM_001284314 NM_021402
OMIM
CCDS CCDS19050 CCDS19051 CCDS71536
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca