Homo sapiens Gene: GAL3ST2
Summary
InnateDB Gene IDBG-85321.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAL3ST2
Gene Name galactose-3-O-sulfotransferase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154252
Encoded Proteins
galactose-3-O-sulfotransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 and type 2 (Galbeta 1-3/1-4GlcNAc-R) oligosaccharides with similar efficiencies, and on core 1 glycans. This enzyme has been implicated in tumor metastasis processes. This gene is different from the GAL3ST3 gene located on chromosome 11, which has also been referred to as GAL3ST2 and encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:241776825-241804208
Strand Forward strand
Band q37.3
Transcripts
ENST00000192314 ENSP00000192314
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001733 galactosylceramide sulfotransferase activity
GO:0008146 sulfotransferase activity
Biological Process
GO:0008150 biological_process
GO:0009058 biosynthetic process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q9H3Q3
TrEMBL
UniProt Splice Variant
Entrez Gene 64090
UniGene Hs.632556
RefSeq NM_022134
HUGO HGNC:24869
OMIM 608237
CCDS CCDS33427
HPRD
IMGT
EMBL AB040610 AC114730 BC117293 BC117295 CH471063
GenPept AAI17294 AAI17296 AAX82021 BAB16844 EAW71293
RNA Seq Atlas 64090