Version 5.4
Homo sapiens Gene: ZDHHC9
Summary
InnateDB Gene IDBG-85713.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZDHHC9
Gene Name zinc finger, DHHC-type containing 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188706
Encoded Proteins
IDBP-85717
zinc finger, DHHC-type containing 9
IDBP-85721
zinc finger, DHHC-type containing 9
IDBP-295064
zinc finger, DHHC-type containing 9
IDBP-380779
zinc finger, DHHC-type containing 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:129803288-129843909
Strand Reverse strand
Band q26.1
Transcripts
ENST00000357166 ENSP00000349689
ENST00000371064 ENSP00000360103
ENST00000406492 ENSP00000383991
ENST00000433917 ENSP00000406165
ENST00000491039
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016409 palmitoyltransferase activity
GO:0019706 protein-cysteine S-palmitoyltransferase activity
GO:0043849 Ras palmitoyltransferase activity
Biological Process
GO:0008152 metabolic process
GO:0018230 peptidyl-L-cysteine S-palmitoylation
GO:0018345 protein palmitoylation
Cellular Component
GO:0002178 palmitoyltransferase complex
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0031228 intrinsic component of Golgi membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036985
View Gene Order
ENSBTAG00000015354
Not yet available
Cross-References
SwissProt Q9Y397
TrEMBL Q5JYE8
UniProt Splice Variant
Entrez Gene 51114
UniGene Hs.193566 Hs.712158
RefSeq NM_001008222 NM_016032
HUGO HGNC:18475
OMIM 300646
CCDS CCDS35395
HPRD
IMGT
EMBL AB209807 AF151847 AK001424 AK001524 AL034405 AL161962 AL359542 AY358558 AY952881 BC000035 BC003128 BC006200 BC012826 CH471107
GenPept AAD34084 AAH00035 AAH03128 AAH06200 AAH12826 AAQ88922 ACF60379 BAA91683 BAA91740 BAD93044 CAB82308 CAI42069 CAI42905 EAX11823 EAX11824 EAX11825
RNA Seq Atlas 51114

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca