Version 5.4
Homo sapiens Gene: NCR2
Summary
InnateDB Gene IDBG-86656.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCR2
Gene Name natural cytotoxicity triggering receptor 2
Synonyms CD336; dJ149M18.1; LY95; NK-p44; NKP44
Species Homo sapiens
Ensembl Gene ENSG00000096264
Encoded Proteins
IDBP-86658
natural cytotoxicity triggering receptor 2
IDBP-86660
natural cytotoxicity triggering receptor 2
IDBP-86662
natural cytotoxicity triggering receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:41335655-41350887
Strand Forward strand
Band p21.1
Transcripts
ENST00000373089 ENSP00000362181
ENST00000373086 ENSP00000362178
ENST00000373083 ENSP00000362175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0045087 innate immune response
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_147694
DAP12 interactions pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
KEGG
hsa04650
Natural killer cell mediated cytotoxicity pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.194721
RefSeq NM_001199509 NM_001199510 NM_004828
HUGO
OMIM
CCDS CCDS4855 CCDS56428 CCDS56429
HPRD 05168
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca