Version 5.4
Homo sapiens Gene: HES3
Summary
InnateDB Gene IDBG-87565.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HES3
Gene Name hairy and enhancer of split 3 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173673
Encoded Proteins
IDBP-87569
hairy and enhancer of split 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:6244192-6245578
Strand Forward strand
Band p36.31
Transcripts
ENST00000377898 ENSP00000367130
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008134 transcription factor binding
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001701 in utero embryonic development
GO:0006351 transcription, DNA-templated
GO:0021555 midbrain-hindbrain boundary morphogenesis
GO:0021557 oculomotor nerve development
GO:0021558 trochlear nerve development
GO:0021575 hindbrain morphogenesis
GO:0021915 neural tube development
GO:0030901 midbrain development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050767 regulation of neurogenesis
GO:0060164 regulation of timing of neuron differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028946
View Gene Order
ENSBTAG00000024525
Not yet available
Cross-References
SwissProt Q5TGS1
TrEMBL
UniProt Splice Variant
Entrez Gene 390992
UniGene
RefSeq NM_001024598
HUGO HGNC:26226
OMIM 609971
CCDS CCDS41238
HPRD 18618
IMGT
EMBL AL031847
GenPept CAI19439
RNA Seq Atlas 390992

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca