Version 5.4
Homo sapiens Gene: HTATSF1
Summary
InnateDB Gene IDBG-87617.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HTATSF1
Gene Name HIV-1 Tat specific factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102241
Encoded Proteins
IDBP-87621
HIV-1 Tat specific factor 1
IDBP-381734
HIV-1 Tat specific factor 1
IDBP-381737
HIV-1 Tat specific factor 1
IDBP-584020
HIV-1 Tat specific factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:136497079-136512346
Strand Forward strand
Band q26.3
Transcripts
ENST00000218364 ENSP00000218364
ENST00000448450 ENSP00000411381
ENST00000425695 ENSP00000412420
ENST00000535601 ENSP00000442699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 35 [view]
Protein-Protein 35 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0019079 viral genome replication
GO:0032784 regulation of DNA-templated transcription, elongation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000067873
View Gene Order
ENSBTAG00000032711
Not yet available
Cross-References
SwissProt O43719
TrEMBL Q5H918 Q5H919
UniProt Splice Variant
Entrez Gene 27336
UniGene Hs.204475 Hs.605934
RefSeq NM_001163280 NM_014500 XM_005262404
HUGO HGNC:5276
OMIM 300346
CCDS CCDS14657
HPRD
IMGT
EMBL AB209303 BC009896 BT006886 CH471150 U76992 Z97632
GenPept AAB18823 AAH09896 AAP35532 BAD92540 CAB10730 EAW88468 EAW88469
RNA Seq Atlas 27336

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca