Version 5.4
Homo sapiens Gene: HES2
Summary
InnateDB Gene IDBG-87661.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HES2
Gene Name hairy and enhancer of split 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000069812
Encoded Proteins
IDBP-87663
hairy and enhancer of split 2 (Drosophila)
IDBP-87665
hairy and enhancer of split 2 (Drosophila)
IDBP-87667
hairy and enhancer of split 2 (Drosophila)
IDBP-721684
IDBP-722477
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:6412418-6424670
Strand Reverse strand
Band p36.31
Transcripts
ENST00000377837 ENSP00000367068
ENST00000377836 ENSP00000367067
ENST00000377834 ENSP00000367065
ENST00000471190
ENST00000487437 ENSP00000465248
ENST00000489730 ENSP00000465270
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0008134 transcription factor binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028940
View Gene Order
ENSBTAG00000021210
Not yet available
Cross-References
SwissProt Q9Y543
TrEMBL
UniProt Splice Variant
Entrez Gene 54626
UniGene Hs.118727 Hs.624669 Hs.734685
RefSeq NM_019089
HUGO HGNC:16005
OMIM 609970
CCDS CCDS30574
HPRD 13649
IMGT
EMBL AK091122 AL031848 BC012091 BC132698 BC136963 BC142687 CH471130
GenPept AAH12091 AAI32699 AAI36964 AAI42688 BAG52286 CAB46198 CAB46199 EAW71533
RNA Seq Atlas 54626

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca