Version 5.4
Homo sapiens Gene: FBXL15
Summary
InnateDB Gene IDBG-87962.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL15
Gene Name F-box and leucine-rich repeat protein 15
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000107872
Encoded Proteins
IDBP-87964
F-box and leucine-rich repeat protein 15
IDBP-87966
F-box and leucine-rich repeat protein 15
IDBP-384906
F-box and leucine-rich repeat protein 15
IDBP-384909
F-box and leucine-rich repeat protein 15
IDBP-384913
F-box and leucine-rich repeat protein 15
IDBP-384914
F-box and leucine-rich repeat protein 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:102419189-102423136
Strand Forward strand
Band q24.32
Transcripts
ENST00000224862 ENSP00000224862
ENST00000369956 ENSP00000358972
ENST00000432590 ENSP00000411435
ENST00000457067 ENSP00000392215
ENST00000440407 ENSP00000405961
ENST00000425536 ENSP00000403646
ENST00000481808
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0009953 dorsal/ventral pattern formation
GO:0016567 protein ubiquitination
GO:0030282 bone mineralization
GO:0030513 positive regulation of BMP signaling pathway
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025226
View Gene Order
ENSBTAG00000002500
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.380081 Hs.617467
RefSeq NM_024326 XM_005270150 XM_005270151
HUGO
OMIM
CCDS CCDS31273
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca