Homo sapiens Gene: AGMO
Summary
InnateDB Gene IDBG-8847.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGMO
Gene Name alkylglycerol monooxygenase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000187546
Encoded Proteins
alkylglycerol monooxygenase
alkylglycerol monooxygenase
alkylglycerol monooxygenase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:15200318-15562015
Strand Reverse strand
Band p21.2
Transcripts
ENST00000342526 ENSP00000341662
ENST00000407277 ENSP00000385742
ENST00000418075 ENSP00000394412
ENST00000498264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0050479 glyceryl-ether monooxygenase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0006643 membrane lipid metabolic process
GO:0046485 ether lipid metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.670634
RefSeq NM_001004320 XM_006715731
HUGO
OMIM
CCDS CCDS34604
HPRD 13362
IMGT
EMBL
GenPept
RNA Seq Atlas