Version 5.4
Homo sapiens Protein: AGMO
Summary
InnateDB Protein IDBP-8849.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGMO
Protein Name alkylglycerol monooxygenase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000341662
InnateDB Gene IDBG-8847 (AGMO)
Protein Structure
UniProt Annotation
Function Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes. {ECO:0000269PubMed:20643956}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:20643956}; Multi-pass membrane protein {ECO:0000269PubMed:20643956}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0050479 glyceryl-ether monooxygenase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0006643 membrane lipid metabolic process
GO:0046485 ether lipid metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006694 Fatty acid hydroxylase
PFAM PF04116
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZNB7
PhosphoSite PhosphoSite-Q6ZNB7
TrEMBL X5D773
UniProt Splice Variant
Entrez Gene 392636
UniGene Hs.670634
RefSeq NP_001004320
HUGO HGNC:33784
OMIM 613738
CCDS CCDS34604
HPRD 13362
IMGT
EMBL AK131284 BC108676 CH236948 KJ534765
GenPept AAI08677 AHW56405 BAD18458 EAL24290

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca