Version 5.4
Homo sapiens Gene: DDX31
Summary
InnateDB Gene IDBG-90318.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDX31
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000125485
Encoded Proteins
IDBP-90322
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
IDBP-90324
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
IDBP-90326
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
IDBP-383074
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
IDBP-811466
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:132592997-132670401
Strand Reverse strand
Band q34.13
Transcripts
ENST00000372155
ENST00000372159 ENSP00000361232
ENST00000372153 ENSP00000361226
ENST00000310532 ENSP00000310539
ENST00000438527 ENSP00000387730
ENST00000480876 ENSP00000479697
ENST00000482620
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026806
View Gene Order
ENSBTAG00000003530
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 64794
UniGene
RefSeq NM_022779 NM_138620 XM_005272207 XM_005272208
HUGO HGNC:16715
OMIM
CCDS CCDS6951 CCDS6952
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 64794

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca