InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDX31

Summary

InnateDB Protein

IDBP-90326.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDX31

Protein Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 31

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000310539

InnateDB Gene

IDBG-90318 (DDX31)

Protein Structure

UniProt Annotation

Function

Probable ATP-dependent RNA helicase. {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000269PubMed:12429849}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006200

ATP catabolic process

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

InterPro

IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00270

PRINTS

PIRSF

SMART

SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9H8H2

PhosphoSite

PhosphoSite-Q9H8H2

TrEMBL

UniProt Splice Variant

Entrez Gene

64794

UniGene

Hs.660767

RefSeq

NP_619526

HUGO

HGNC:16715

OMIM

CCDS

CCDS6952

HPRD

10860

IMGT

EMBL

AF335567 AF335568 AF335569 AF427339 AK023695 AK027002 AK027484 AL160165 AL354735 BC012726

GenPept

AAH12726 AAL26549 AAQ14888 AAQ14889 AAQ14890 BAB14644 BAB15620 BAB55146 CAH70530 CAH70531 CAH70532 CAI16564 CAI16565