Version 5.4
Homo sapiens Gene: S100P
Summary
InnateDB Gene IDBG-9072.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100P
Gene Name S100 calcium binding protein P
Synonyms MIG9
Species Homo sapiens
Ensembl Gene ENSG00000163993
Encoded Proteins
IDBP-9074
S100 calcium binding protein P
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:6693069-6697170
Strand Forward strand
Band p16.1
Transcripts
ENST00000296370 ENSP00000296370
ENST00000513778
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0048306 calcium-dependent protein binding
GO:0050786 RAGE receptor binding
Biological Process
GO:0010033 response to organic substance
GO:0043542 endothelial cell migration
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031528 microvillus membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P25815
TrEMBL
UniProt Splice Variant
Entrez Gene 6286
UniGene
RefSeq NM_005980
HUGO HGNC:10504
OMIM 600614
CCDS CCDS3391
HPRD
IMGT
EMBL AF539739 AY423724 BC006819 BT007289 X65614
GenPept AAH06819 AAO41114 AAP35953 AAS00487 CAA46566
RNA Seq Atlas 6286

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca