Version 5.4
Homo sapiens Gene: COL21A1
Summary
InnateDB Gene IDBG-91221.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COL21A1
Gene Name collagen, type XXI, alpha 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124749
Encoded Proteins
IDBP-91223
collagen, type XXI, alpha 1
IDBP-91225
collagen, type XXI, alpha 1
IDBP-91227
collagen, type XXI, alpha 1
IDBP-381996
collagen, type XXI, alpha 1
IDBP-595197
collagen, type XXI, alpha 1
IDBP-587847
collagen, type XXI, alpha 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes the alpha chain of type XXI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XXI collagen is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. An alternatively spliced transcript variant has been described, but its full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:56056590-56394094
Strand Reverse strand
Band p12.1
Transcripts
ENST00000370819 ENSP00000359855
ENST00000370817 ENSP00000359853
ENST00000244728 ENSP00000244728
ENST00000456983 ENSP00000390958
ENST00000488912 ENSP00000433624
ENST00000467045
ENST00000467216
ENST00000482933
ENST00000461489
ENST00000484987
ENST00000469682
ENST00000535941 ENSP00000444384
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005581 collagen trimer
GO:0005788 endoplasmic reticulum lumen
GO:0031012 extracellular matrix
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_121139
Collagen biosynthesis and modifying enzymes pathway
REACT_118779
Extracellular matrix organization pathway
REACT_120729
Collagen formation pathway
KEGG
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.47629 Hs.645200
RefSeq NM_030820 XM_006715225
HUGO
OMIM
CCDS CCDS55025
HPRD 09884
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca