Version 5.4
Homo sapiens Gene: DNASE1L1
Summary
InnateDB Gene IDBG-91292.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNASE1L1
Gene Name deoxyribonuclease I-like 1
Synonyms DNAS1L1; DNASEX; DNL1L; G4.8; XIB
Species Homo sapiens
Ensembl Gene ENSG00000013563
Encoded Proteins
IDBP-91294
deoxyribonuclease I-like 1
IDBP-91296
deoxyribonuclease I-like 1
IDBP-91298
deoxyribonuclease I-like 1
IDBP-91300
deoxyribonuclease I-like 1
IDBP-91302
deoxyribonuclease I-like 1
IDBP-243209
deoxyribonuclease I-like 1
IDBP-383558
deoxyribonuclease I-like 1
IDBP-383559
deoxyribonuclease I-like 1
IDBP-383560
deoxyribonuclease I-like 1
IDBP-383562
deoxyribonuclease I-like 1
IDBP-383566
deoxyribonuclease I-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:154401238-154412112
Strand Reverse strand
Band q28
Transcripts
ENST00000369809 ENSP00000358824
ENST00000014935 ENSP00000014935
ENST00000369808 ENSP00000358823
ENST00000369807 ENSP00000358822
ENST00000309585 ENSP00000309168
ENST00000393638 ENSP00000377255
ENST00000447892 ENSP00000395591
ENST00000451865 ENSP00000393346
ENST00000412184 ENSP00000416881
ENST00000424626 ENSP00000393000
ENST00000432135 ENSP00000410281
ENST00000497242
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004536 deoxyribonuclease activity
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006259 DNA metabolic process
GO:0006308 DNA catabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019088
View Gene Order
ENSBTAG00000007455
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.401929
RefSeq NM_001009932 NM_001009933 NM_001009934 NM_006730 XM_005277829
HUGO
OMIM
CCDS CCDS14747
HPRD 02096
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca